insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
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Why does this happen? Blood sugar spikes: Refined carbohydrates in UPFs cause rapid glucose surges, leading to insulin resistance over time. Ximena Araya-Fischel, Forbes, 25 Mar. 2025 Research shows that consuming healthy fats like olive oil can reduce appetite and improve insulin resistance. Carrie Madormo, Rn, Mph, Verywell Health, 18 Mar. 2025 Over time, inflammation in the body can contribute to insulin resistance as well. Sara Novak, Discover Magazine, 14 Mar. 2025 Sedentary lifestyles: Lack of regular physical activity has been linked to obesity, insulin resistance and chronic inflammation, all of which can contribute to colorectal cancer. Kailey Asetov, Miami Herald, 11 Mar. 2025 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 1 Apr. 2025.

Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
Last Updated: - Updated example sentences
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